Outcomes and Decision Making in High-Risk Lap and NoLap Patients: Clinical Frailty Score vs NELA Score Clinical Frailty Score should be used in conjunction with NELA to aid decision making.

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R Bradley
https://orcid.org/0000-0002-7745-9835
A Krishna
G John
M Hamza
C Blatchford
J Wohlgemut
I Nikolopoulos

Abstract

Introduction: High-risk emergency laparotomy patients are characterised as having a National Emergency Laparotomy Audit (NELA) mortality prediction of ≥5%, but this often underestimates risk. Frailty has been reported as an important factor in decision-making for laparotomy. Outcomes for patients who do not proceed to laparotomy (NoLap) are less-reported, as are the reasons why this decision is made.  Our aim was to explore the decision making process for high-risk patients eligible for laparotomy and to investigate which factors heavily influenced the decision. We then analysed outcomes in those were managed with a laparotomy (Lap), vs NoLap.


Methods: A prospective study over 6 months was conducted across two hospitals. Patients with NELA ≥5% and aged ≥65 warranting laparotomy were included.  Fisher's and Mann-Whitney U testing was used to compare Lap and NoLap outcomes. Multivariable regression analysis was used to determine which factors were associated with the decision for or against laparotomy. 


Results: A total of 62 patients were eligible for inclusion. NoLap patients had significantly higher NELA (p=<0.001), American Society of Anaesthesiologists (ASA) classification (p=0.008) CFS (p=<0.001), and higher mortalities (<0.001). ASA was the only predictor of mortality (p=0.04). Only 32% of all cases had a full multidisciplinary team (intensivist, anaesthesiologist and surgeon) involved in decision-making. CFS was the most specific and sensitive factor influencing decision-making (p=<0.001), but only NELA predicted morbidity (p=0.03). 


Conclusions: High-risk NoLap patients have worse outcomes than their Lap counterparts. Although CFS is not currently included in the NELA calculation, it is a crucial variable used in laparotomy decision making in high-risk patients. 

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How to Cite
Bradley, R., Krishna, A., John, G., Hamza, M., Blatchford, C., Wohlgemut, J., & Nikolopoulos, I. (2025). Outcomes and Decision Making in High-Risk Lap and NoLap Patients: Clinical Frailty Score vs NELA Score: Clinical Frailty Score should be used in conjunction with NELA to aid decision making . British Journal Of Surgical Science, 5(1). https://doi.org/10.54323/bjoss.2025.42
Section
GENERAL SURGERY

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